Description

2-Bromo-n-(Piperidine-4-Yl)Benzamido Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1233958-32-1. This compound is a critical building block in modern medicinal chemistry, valued for its unique piperidine-benzamide scaffold which is integral to the synthesis of bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Development: The structural motif is relevant for designing inhibitors of specific enzymes.
• Kinase Inhibitor Synthesis: Serves as a core fragment in the creation of compounds targeting kinase enzymes involved in cell signaling.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological processes and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.

Basic Information

Product Name	2-Bromo-n-(Piperidine-4-Yl)Benzamido Hydrochloride
CAS No.	1233958-32-1
Molecular Formula	C13H16BrN2O • HCl
Molecular Weight	347.65 g/mol (Free base: 311.19 g/mol)
Synonyms	2-Bromo-N-(piperidin-4-yl)benzamide hydrochloride; 4-[(2-Bromobenzoyl)amino]piperidine hydrochloride; 2-Bromo-N-(4-piperidinyl)benzamide monohydrochloride; Benzamide, 2-bromo-N-(4-piperidinyl)-, hydrochloride (1:1); 1233958-32-1; UNII-7F8K7J5S0H; 7F8K7J5S0H
EINECS	Contact for details

Quality Control

Our 2-Bromo-n-(Piperidine-4-Yl)Benzamido Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.