Description

tert-Butyl 4-[(Tetrahydro-2H-Pyran-4-Carbonyl)Amino]Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for research and development in medicinal chemistry, serving as a key building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves as a key building block in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the synthesis of specialized molecules used to study biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific projects.
• Academic Research: Utilized in university and institutional labs for advanced synthetic methodology development and novel compound library generation.

Basic Information

Product Name	tert-Butyl 4-[(Tetrahydro-2H-Pyran-4-Carbonyl)Amino]Piperidine-1-Carboxylate
CAS No.	1233955-29-7
Molecular Formula	C16H28N2O4
Molecular Weight	312.41 g/mol
Synonyms	1-Boc-4-[(Tetrahydro-2H-pyran-4-carbonyl)amino]piperidine; 1-(tert-Butoxycarbonyl)-4-[(oxane-4-carbonyl)amino]piperidine; 4-[(Tetrahydro-2H-pyran-4-carbonyl)amino]-1-piperidinecarboxylic acid tert-butyl ester; tert-Butyl 4-(tetrahydro-2H-pyran-4-ylcarbonylamino)piperidine-1-carboxylate; 1-Boc-4-(tetrahydropyran-4-carboxamido)piperidine; Boc-4-(THP-4-carboxamido)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(Tetrahydro-2H-Pyran-4-Carbonyl)Amino]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.