Description

2-Cyano-6-Bromobenzylbromide is a versatile brominated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a cyano and a benzyl bromide functional group, makes it a critical precursor for constructing complex heterocycles and pharmaceutical intermediates. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to facilitate key carbon-carbon and carbon-heteroatom bond-forming reactions.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzyl or aryl nitrile motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bromobenzyl moiety is incorporated.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or non-linear optical (NLO) chromophores.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.
• Nucleophilic Substitution: The benzyl bromide group is highly reactive towards various nucleophiles, enabling the introduction of diverse functional groups.

Basic Information

Product Name	2-Cyano-6-Bromobenzylbromide
CAS No.	1233479-42-9
Molecular Formula	C9H5Br2N
Molecular Weight	286.95 g/mol
Synonyms	6-Bromo-2-(bromomethyl)benzonitrile; 2-Bromomethyl-6-bromobenzonitrile; (6-Bromo-2-cyanophenyl)methyl bromide; α-Bromo-6-bromo-o-tolunitrile; 1-Bromo-2-(bromomethyl)-3-cyanobenzene; 2-Cyano-6-bromobenzyl bromide; 6-Bromo-2-cyanobenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-6-Bromobenzylbromide is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.