Description

2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-value, synthetically versatile boronic ester derivative. This compound is a critical building block in modern organic synthesis, prized for its role in facilitating carbon-carbon bond formation. It is primarily utilized by pharmaceutical R&D and agrochemical scientists for the development of novel active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in drug candidates and functional materials.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex molecules for oncology, CNS, and antiviral research programs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis.
• Material Science Research: A building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	1231892-37-7
Molecular Formula	C14H18BNO2
Molecular Weight	243.11 g/mol
Synonyms	2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 3-Cyano-2-methylphenylboronic acid pinacol ester; (3-Cyano-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-3-(pinacolatoboryl)benzonitrile; Pinacol (3-cyano-2-methylphenyl)boronate; 2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile CAS 1231892-37-7
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.