Description

1-(Trifluoromethyl)Cyclopropanecarbaldehyde is a high-value fluorinated building block characterized by its reactive aldehyde group and cyclopropane ring. This compound matters for its unique ability to introduce both trifluoromethyl and cyclopropane motifs into target molecules, significantly altering their physicochemical and biological properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty monomers and polymers, contributing to materials with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Exploration: A valuable substrate for studying new fluorination reactions and the behavior of strained ring systems under various conditions.

Basic Information

Product Name	1-(Trifluoromethyl)Cyclopropanecarbaldehyde
CAS No.	1229311-61-8
Molecular Formula	C5H5F3O
Molecular Weight	138.09 g/mol
Synonyms	1-(Trifluoromethyl)cyclopropanecarboxaldehyde; (Trifluoromethyl)cyclopropanecarbaldehyde; Cyclopropanecarbaldehyde, 1-(trifluoromethyl)-; 1-(Trifluoromethyl)cyclopropane-1-carbaldehyde; α-(Trifluoromethyl)cyclopropanecarbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(Trifluoromethyl)Cyclopropanecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.