Description

2,5-Difluoro-4-Formylphenylphenylboronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl group and a boronic acid moiety on a difluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced fungicides and herbicides by incorporating the difluorophenyl moiety into active molecules.
• Material Science: Serves as a monomer or linker in the synthesis of organic electronic materials, such as OLEDs and OFETs.
• Chemical Biology: Employed in the development of chemical probes and sensors that utilize boronic acid-diol interactions.
• Ligand Synthesis: The formyl group allows for further functionalization to create novel ligands for catalysis.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in R&D laboratories worldwide.

Basic Information

Product Name	2,5-Difluoro-4-Formylphenylphenylboronic Acid
CAS No.	1228828-19-0
Molecular Formula	C13H9BF2O3
Molecular Weight	262.02 g/mol
Synonyms	2,5-Difluoro-4-formylbenzeneboronic Acid; (4-Formyl-2,5-difluorophenyl)boronic Acid; 2,5-Difluoro-4-formylphenylboronic Acid; 4-Borono-2,5-difluorobenzaldehyde; 2,5-Difluoro-4-formylbenzeneboronic Acid Pinacol Ester (common precursor); 4-Formyl-2,5-difluorophenylboronic Acid; 2,5-Difluoro-4-formylphenyl-B(OH)2; 4-Carbaldehyde-2,5-difluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-Formylphenylphenylboronic Acid is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.