Description

(R)-tert-Butyl 6-Oxopiperidin-3-Ylcarbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, where stereochemical integrity is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel APIs, particularly for central nervous system (CNS) and metabolic disorder treatments.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex, enantiomerically pure molecules in medicinal chemistry and process development.
• Protease Inhibitor Research: Used in the synthesis of potential inhibitors targeting specific enzymatic pathways.
• Agrochemical Development: Employed as a building block for creating chiral active ingredients with enhanced efficacy and environmental profile.
• Academic & Contract Research: A valuable reagent for synthetic organic chemistry research in universities and CROs (Contract Research Organizations).
• Custom Synthesis: A starting material for the contract manufacturing of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	(R)-tert-Butyl 6-Oxopiperidin-3-Ylcarbamate
CAS No.	1228566-94-6
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	(R)-tert-Butyl 6-oxopiperidin-3-ylcarbamate; (3R)-6-Oxo-3-piperidinyl carbamic acid 1,1-dimethylethyl ester; (R)-N-Boc-6-oxopiperidin-3-amine; tert-Butyl (R)-6-oxopiperidin-3-ylcarbamate; (R)-N-Boc-3-amino-6-piperidone; (R)-3-Amino-6-piperidone N-Boc; (R)-3-((tert-Butoxycarbonyl)amino)piperidin-2-one; (R)-Boc-3-Amino-δ-valerolactam
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 6-Oxopiperidin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.