Description

Gabapentin Quaternary Salt (Iodide) is a chemically modified derivative of the widely used pharmaceutical compound Gabapentin, specifically functionalized as a quaternary ammonium salt with an iodide counterion. This modification enhances its physicochemical properties, making it a valuable intermediate for advanced pharmaceutical research and the development of novel drug delivery systems. It is primarily sought by researchers and manufacturers in the pharmaceutical and life science sectors for applications in medicinal chemistry, prodrug synthesis, and as a reference standard.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel gabapentin prodrugs and analogs with improved bioavailability or targeted release profiles.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic applications for gabapentin-related compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Ion-Pairing Agent: Its quaternary ammonium structure can be utilized in analytical chemistry as an ion-pairing reagent for chromatography.
• Bioconjugation Studies: Potential use in creating conjugates for targeted drug delivery due to its reactive quaternary ammonium group.
• Academic & Industrial R&D: Fundamental research in neuropharmacology and the development of new chemical entities (NCEs).

Basic Information

Product Name	Gabapentin Quaternary Salt (Iodide)
CAS No.	1228301-72-1
Molecular Formula	C13H25IN2O2
Molecular Weight	392.26 g/mol
Synonyms	1-((Isobutylamino)methyl)cyclohexaneacetic acid quaternary ammonium iodide salt; Gabapentin quaternary ammonium iodide; Gabapentin N-alkyl iodide; Gabapentinium salt; [1-(Aminomethyl)cyclohexyl]acetic acid isobutylammonium iodide derivative; (3-Isobutyl-gaba) quaternary iodide; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Gabapentin Quaternary Salt (Iodide) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.