Description

3-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the biaryl motif is a common structural feature.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and in the development of new catalytic systems.
• Chemical Biology & Diagnostics: Utilized in the synthesis of molecular probes, sensors, and other tools for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid
CAS No.	1228181-35-8
Molecular Formula	C10H12BClO3
Molecular Weight	226.46 g/mol
Synonyms	[3-Chloro-4-(cyclopropylmethoxy)phenyl]boronic acid; (3-Chloro-4-cyclopropylmethoxyphenyl)boronic Acid; 3-Chloro-4-(cyclopropylmethoxy)benzeneboronic Acid; B-[3-Chloro-4-(cyclopropylmethoxy)phenyl]boronic Acid; 1228181-35-8; 3-Chloro-4-cyclopropylmethoxybenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.