Description

Mifepristone D6 CAS NO 1228097-18-4 is a deuterium-labeled internal standard of the synthetic steroid mifepristone, specifically designed for use in quantitative analytical methods. This high-purity compound is essential for ensuring accuracy and reliability in mass spectrometry-based assays, where it corrects for variations in sample preparation and instrument response. It is a critical tool for pharmaceutical researchers, clinical laboratories, and forensic toxicologists engaged in drug metabolism studies, pharmacokinetic analysis, and bioanalytical method development.

Application

• Quantitative Bioanalysis: Serves as a stable isotope-labeled internal standard in LC-MS/MS and GC-MS methods for the precise quantification of mifepristone and its metabolites in biological matrices (e.g., plasma, serum, urine).
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Forensic and Clinical Toxicology: Used in confirmatory testing and therapeutic drug monitoring to ensure reliable and legally defensible results.
• Pharmaceutical R&D: Supports method validation, stability testing, and impurity profiling during drug development and quality control processes.
• Reference Material Production: Acts as a certified component in the preparation of calibrated reference standards and proficiency testing materials.

Basic Information

Product Name	Mifepristone D6
CAS No.	1228097-18-4
Molecular Formula	C29H29D6NO5
Molecular Weight	~ 485.6 g/mol
Synonyms	11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17α-(1-propynyl)-estra-4,9-dien-3-one D6; RU-486 D6; Mifegyne D6; 11β-(4-Dimethylaminophenyl)-17β-hydroxy-17α-(prop-1-ynyl)-estra-4,9-dien-3-one D6; Deuterated Mifepristone; Mifepristone-d6; [D6]-Mifepristone
EINECS	Contact for details

Quality Control

Our Mifepristone D6 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and Mass Spectrometry for structural confirmation and isotopic purity, and HPLC for chemical purity assessment. We guarantee high chemical and isotopic purity suitable for sensitive analytical applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.