Description

3-(1H-Pyrrol-1-Yl)-5-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is a high-value, multi-functional heterocyclic organic compound. This specialized chemical serves as a critical advanced intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for its unique structural features, including the benzothiophene core, trifluoromethyl group, and carbohydrazide moiety.

Application

• Pharmaceutical Intermediate: Key building block for the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, leveraging the biological activity of the benzothiophene scaffold.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of organic semiconductors, liquid crystals, and specialty polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a tool compound in biochemical assays.
• Custom Synthesis & Contract Manufacturing: A pivotal intermediate for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	3-(1H-Pyrrol-1-Yl)-5-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide
CAS No.	1227955-18-1
Molecular Formula	C14H10F3N3OS
Molecular Weight	325.31 g/mol
Synonyms	5-(Trifluoromethyl)-3-(1H-pyrrol-1-yl)-1-benzothiophene-2-carbohydrazide; 3-(1H-Pyrrol-1-yl)-5-(trifluoromethyl)benzo[b]thiophene-2-carbohydrazide; 1-Benzothiophene-2-carbohydrazide, 3-(1H-pyrrol-1-yl)-5-(trifluoromethyl)-; 1227955-18-1; 3-Pyrrol-1-yl-5-trifluoromethyl-1-benzothiophene-2-carbohydrazide
EINECS	Contact for details

Quality Control

Our 3-(1H-Pyrrol-1-Yl)-5-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.