Description

(E)-N-(3-(3-(Dimethylamino)acryloyl)phenyl)acetamide is a specialized organic compound featuring a conjugated enaminone structure. This molecular architecture makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex heterocyclic systems and pharmacologically active scaffolds. It is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting kinase inhibition or other protein-protein interactions.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) for developing new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex molecules like quinolones, chromones, and other fused heterocycles via cyclization reactions.
• Chemical Reference Standard: Employed as a high-purity standard in analytical method development and quality control for related pharmaceutical processes.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science Precursor: Investigated for use in synthesizing organic semiconductors or photoactive materials due to its conjugated system.

Basic Information

Product Name	(E)-N-(3-(3-(Dimethylamino)acryloyl)phenyl)acetamide
CAS No.	1227694-86-1
Molecular Formula	C15H18N2O2
Molecular Weight	258.32 g/mol
Synonyms	N-[3-[(1E)-3-(Dimethylamino)-1-oxo-2-propen-1-yl]phenyl]acetamide; (E)-3-(Dimethylamino)-1-[3-(acetylamino)phenyl]-2-propen-1-one; (E)-N-(3-(3-(Dimethylamino)acryloyl)phenyl)acetamide; (E)-1-(3-Acetamidophenyl)-3-(dimethylamino)prop-2-en-1-one; 3'-(Acetylamino)-3-(dimethylamino)acrylophenone; (E)-3-(Dimethylamino)-1-(3-acetamidophenyl)prop-2-en-1-one; 1227694-86-1; Enaminone intermediate 1227694-86-1
EINECS	Contact for details

Quality Control

Our (E)-N-(3-(3-(Dimethylamino)acryloyl)phenyl)acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.