Description

Benzamide, 3-Nitro-2-(Trifluoromethyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl and nitro-substituted benzamide structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring molecules with enhanced metabolic stability and bioavailability. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the research and development of new drug candidates, especially in oncology and central nervous system (CNS) therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging the biological activity of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals due to its aromatic and electron-withdrawing substituents.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in academic and industrial R&D.

Basic Information

Product Name	Benzamide, 3-Nitro-2-(Trifluoromethyl)-
CAS No.	1227587-60-1
Molecular Formula	C8H5F3N2O3
Molecular Weight	234.13 g/mol
Synonyms	3-Nitro-2-(trifluoromethyl)benzamide; 2-(Trifluoromethyl)-3-nitrobenzamide; Benzamide, 2-(trifluoromethyl)-3-nitro-; 3-Nitro-α,α,α-trifluoro-o-toluamide; 2-Trifluoromethyl-3-nitrobenzamide; 3-Nitro-2-trifluoromethylbenzamide; o-(Trifluoromethyl)-m-nitrobenzamide
EINECS	Contact for details

Quality Control

Our production of Benzamide, 3-Nitro-2-(Trifluoromethyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure compliance with customer specifications and industry standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.