Description

2-Nitro-6-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring both nitro and trifluoromethyl substituents. This compound matters for its unique electronic properties and structural framework, which are critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Functional Dye & Pigment Production: Employed in the synthesis of specialized dyes and pigments that require nitro and cyano groups for color and fastness properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for constructing complex biaryl structures.
• Chemical Research & Development: Utilized in academic and industrial R&D settings for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Detail
Product Name	2-Nitro-6-(Trifluoromethyl)Benzonitrile
CAS No.	1227581-80-7
Molecular Formula	C8H3F3N2O2
Molecular Weight	216.12 g/mol
Synonyms	2-Nitro-α,α,α-trifluoro-o-tolunitrile; 6-(Trifluoromethyl)-2-nitrobenzonitrile; 2-Nitro-6-trifluoromethylbenzonitrile; Benzonitrile, 2-nitro-6-(trifluoromethyl)-; o-Nitro-α,α,α-trifluorotoluonitrile; 2-Cyano-3-nitrobenzotrifluoride
EINECS	Contact for details

Quality Control

Every batch of 2-Nitro-6-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to the presence of nitro and nitrile groups, store separately from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.