Description

Benzonitrile, 3-Nitro-2-(Trifluoromethyl)- is a high-purity, multi-functional aromatic nitrile building block distinguished by its nitro and trifluoromethyl substituents. This compound is engineered to provide exceptional reactivity and stability for advanced chemical synthesis, enabling the development of novel materials and active ingredients. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated aromatic systems into their products.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Polymer & Resin Modifier: Employed to introduce polar nitrile and electron-withdrawing groups into polymer backbones, altering thermal and mechanical properties.
• Dye & Pigment Intermediate: Facilitates the creation of novel, high-performance colorants with specific light-fastness and solubility characteristics.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) in medicinal and process chemistry research.

Basic Information

Product Name	Benzonitrile, 3-Nitro-2-(Trifluoromethyl)-
CAS No.	1227516-56-4
Molecular Formula	C8H3F3N2O2
Molecular Weight	216.12 g/mol
Synonyms	3-Nitro-2-(trifluoromethyl)benzonitrile; 2-(Trifluoromethyl)-3-nitrobenzonitrile; 3-Nitro-α,α,α-trifluoro-o-tolunitrile; Benzonitrile, 3-nitro-2-(trifluoromethyl)-; o-Cyano-α,α,α-trifluoro-m-nitrobenzene
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 3-Nitro-2-(Trifluoromethyl)- is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.