Description

4-Cyano-3-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its benzoic acid core substituted with both a cyano and a trifluoromethyl group. This unique molecular architecture makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing polar components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering physical properties for specialty coatings and high-performance plastics.
• Chemical Research & Development: A versatile reagent for organic synthesis, enabling the exploration of new chemical spaces in medicinal and materials chemistry.
• Ligand & Catalyst Design: Used to create sophisticated ligands for metal-organic frameworks (MOFs) and asymmetric catalysis.

Basic Information

Product Name	4-Cyano-3-(Trifluoromethyl)Benzoic Acid
CAS No.	1227502-36-4
Molecular Formula	C9H4F3NO2
Molecular Weight	215.13 g/mol
Synonyms	3-(Trifluoromethyl)-4-cyanobenzoic Acid; 4-Cyano-3-trifluoromethylbenzoic Acid; Benzoic acid, 4-cyano-3-(trifluoromethyl)-; 2-Cyano-5-carboxybenzotrifluoride; 4-CN-3-CF3-BA; 1227502-36-4; 4-Cyano-α,α,α-trifluoro-m-toluic acid
EINECS	Contact for details

Quality Control

Our 4-Cyano-3-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.