Description

1-Ethyl-4-(Hydroxymethyl)-2-Pyrrolidinone (Saltdata: 0.4H2O 0.07Nacl) is a high-purity, functionalized pyrrolidinone derivative with significant synthetic utility. This compound matters as a versatile chiral building block and intermediate, offering a unique combination of a polar, water-soluble hydroxymethyl group and a lipophilic pyrrolidinone core. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly for neurological and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers, enhancing hydrophilicity and adhesion properties.
• Chemical Research (R&D): Employed in academic and industrial research for exploring new synthetic methodologies and constructing molecular libraries.
• Electrolyte Additive: Potential application as a functional additive in advanced battery electrolytes to improve stability and performance.

Basic Information

Product Name	1-Ethyl-4-(Hydroxymethyl)-2-Pyrrolidinone (Saltdata: 0.4H2O 0.07Nacl)
CAS No.	1227465-53-3
Molecular Formula	C7H13NO2 • 0.4H2O • 0.07NaCl
Molecular Weight	~159.6 (Anhydrous base: 143.18)
Synonyms	4-(Hydroxymethyl)-1-ethyl-2-pyrrolidinone; 1-Ethyl-4-(hydroxymethyl)pyrrolidin-2-one; (4-Hydroxymethyl-1-ethyl-2-pyrrolidinone); N-Ethyl-4-(hydroxymethyl)-2-pyrrolidinone; 2-Pyrrolidinone, 1-ethyl-4-(hydroxymethyl)-; Chiral Hydroxymethyl Pyrrolidinone Derivative; EHMP
EINECS	Contact for details

Quality Control

Our 1-Ethyl-4-(Hydroxymethyl)-2-Pyrrolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	3.0% - 6.0% (Theoretical for 0.4H2O: ~4.5%)
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.