Description

1-(Difluoromethoxy)-2,4-Difluoro-Benzene is a specialized fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique difluoromethoxy and difluoro substitution pattern makes it a valuable precursor for introducing fluorine atoms into complex molecules, which is critical for modulating their physical, chemical, and biological properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorine to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where fluorination enhances efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a fluorinated core component in the synthesis of high-performance liquid crystals for display technologies.
• Organic Electronics: Employed as a building block for fluorinated organic semiconductors and charge-transport materials.
• Advanced Polymer Modification: Used to incorporate fluorine into polymer backbones to enhance chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and creating compound libraries.

Basic Information

Item	Detail
Product Name	1-(Difluoromethoxy)-2,4-Difluoro-Benzene
CAS No.	1226194-39-3
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	2,4-Difluoro-1-(difluoromethoxy)benzene; Benzene, 1-(difluoromethoxy)-2,4-difluoro-; α,α-Difluoro-2,4-difluoroanisole; 2,4-Difluorophenyl difluoromethyl ether; Difluoromethoxy-2,4-difluorobenzene
EINECS	Contact for details

Quality Control

Our 1-(Difluoromethoxy)-2,4-Difluoro-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS and NMR for structural confirmation and impurity profiling. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are kept tightly sealed and at a consistent temperature, ideally between 15-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.