Description

1-(2-Bromo-1-Methyl-Ethoxy)-4-Fluoro-Benzene is a specialized fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive bromoalkyl ether side chain and a fluorine substituent on the benzene ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form new carbon-carbon bonds.
• Etherification & Alkylation Agent: Functions as an alkylating agent in organic synthesis to introduce the 2-bromo-1-methoxyethyl moiety into target molecules.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and the exploration of new chemical spaces in medicinal and materials chemistry.

Basic Information

Product Name	1-(2-Bromo-1-Methyl-Ethoxy)-4-Fluoro-Benzene
CAS No.	1225544-80-8
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	4-Fluoro-1-(2-bromo-1-methoxyethyl)benzene; 1-(2-Bromo-1-methoxyethyl)-4-fluorobenzene; Benzene, 1-(2-bromo-1-methoxyethyl)-4-fluoro-; 4-Fluorophenyl 2-bromo-1-methoxyethyl ether; 2-Bromo-1-(4-fluorophenoxy)-1-methoxyethane
EINECS	Contact for details

Quality Control

Our production of 1-(2-Bromo-1-Methyl-Ethoxy)-4-Fluoro-Benzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO 9001 standards for research and development materials, ensuring reliable quality for critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.