Description

2-(2-Fluoro-Phenyl)-Succinic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where the fluorine atom and succinic acid moiety impart specific biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of advanced polymers and liquid crystals, where fluorinated aromatic compounds modify material properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and condensation reactions.

Basic Information

Product Name	2-(2-Fluoro-Phenyl)-Succinic Acid
CAS No.	1225531-03-2
Molecular Formula	C10H9FO4
Molecular Weight	212.17 g/mol
Synonyms	2-(2-Fluorophenyl)butanedioic acid; (2-Fluorophenyl)succinic acid; 2-(2-Fluorophenyl)-1,4-butanedioic acid; 2-Fluoro-α-phenylsuccinic acid; Succinic acid, 2-(2-fluorophenyl)-; 1225531-03-2; 2-(o-Fluorophenyl)succinic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-Phenyl)-Succinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.