Description

5-(Chloromethyl)Picolinonitrile Hydrochloride is a versatile and high-purity chemical intermediate essential for advanced organic synthesis. This compound is valued for its reactive chloromethyl and nitrile functional groups, which enable precise molecular construction in complex chemical processes. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and functional polymers.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-(Chloromethyl)Picolinonitrile Hydrochloride
CAS No.	1225380-31-3
Molecular Formula	C7H6Cl2N2
Molecular Weight	189.04 g/mol
Synonyms	5-(Chloromethyl)-2-cyanopyridine hydrochloride; 2-Cyano-5-(chloromethyl)pyridine hydrochloride; 5-(Chloromethyl)picolinonitrile HCl; Picolinonitrile, 5-(chloromethyl)-, hydrochloride; 2-Pyridinecarbonitrile, 5-(chloromethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)Picolinonitrile Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP standards for pharmaceutical-grade intermediates, ensuring compliance with global regulatory expectations for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.