Description

1,3-Dibromo-5-Fluoro-2-Isopropoxybenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and functionalized polymers for advanced electronic or optical materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	1,3-Dibromo-5-Fluoro-2-Isopropoxybenzene
CAS No.	1224604-19-6
Molecular Formula	C9H9Br2FO
Molecular Weight	311.97 g/mol
Synonyms	2-Isopropoxy-1,3-dibromo-5-fluorobenzene; 5-Fluoro-1,3-dibromo-2-isopropoxybenzene; Benzene, 1,3-dibromo-5-fluoro-2-(1-methylethoxy)-; 1,3-Dibromo-5-fluoro-2-(propan-2-yloxy)benzene; DBFIPB (abbreviation); 2-(1-Methylethoxy)-1,3-dibromo-5-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-5-Fluoro-2-Isopropoxybenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.