Description

Methyl 3-(5-Methyl-2-(Trifluoromethyl)-1H-Indol-3-Yl)Propanoate CAS NO 1223418-36-7 is a high-value, synthetically versatile indole derivative characterized by its trifluoromethyl and ester functional groups. This compound is a critical advanced intermediate for the research and development of novel pharmaceuticals and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory research.
• Agrochemical Research: Used in developing novel pesticides, herbicides, and fungicides due to the bioactivity-enhancing properties of the trifluoromethyl group.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialized organic electronic materials or ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and exploratory chemistry.

Basic Information

Product Name	Methyl 3-(5-Methyl-2-(Trifluoromethyl)-1H-Indol-3-Yl)Propanoate
CAS No.	1223418-36-7
Molecular Formula	C15H14F3NO2
Molecular Weight	297.27 g/mol
Synonyms	Methyl 3-(5-Methyl-2-(trifluoromethyl)-1H-indol-3-yl)propionate; 3-(5-Methyl-2-(trifluoromethyl)-1H-indol-3-yl)propanoic acid methyl ester; 1H-Indole-3-propanoic acid, 5-methyl-2-(trifluoromethyl)-, methyl ester; Methyl 5-methyl-2-(trifluoromethyl)indole-3-propionate; 1223418-36-7; MFCD30533333
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(5-Methyl-2-(Trifluoromethyl)-1H-Indol-3-Yl)Propanoate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with each shipment, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.