Description

(1S,2S)-2-(Diphenylphosphino)-2,3-Dihydro-1H-Inden-1-Aminiumtetrafluoroborate,Min.97% is a high-purity, chiral phosphine ligand salt, specifically designed for asymmetric catalysis. This compound matters because it provides a stable, air-sensitive ligand precursor that is crucial for achieving high enantioselectivity in transition metal-catalyzed reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for synthesizing chiral intermediates and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Hydrogenation: A key ligand precursor for rhodium or ruthenium catalysts used in the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Enables the production of chiral building blocks for APIs, including those for cardiovascular, neurological, and oncological treatments.
• Asymmetric C-C Bond Formation: Facilitates reactions like allylic alkylation and cross-coupling to construct complex molecular architectures with high optical purity.
• Catalyst Screening & Development: Serves as a critical component in high-throughput screening libraries for discovering new catalytic processes.
• Academic & Industrial R&D: Used in research laboratories for developing novel synthetic methodologies and studying reaction mechanisms.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals, agrochemicals, and flavors & fragrances requiring chiral specificity.

Basic Information

Product Name	(1S,2S)-2-(Diphenylphosphino)-2,3-Dihydro-1H-Inden-1-Aminiumtetrafluoroborate,Min.97%
CAS No.	1222630-42-3
Molecular Formula	C27H26BF4NP
Molecular Weight	473.28 g/mol
Synonyms	(1S,2S)-2-(Diphenylphosphino)-2,3-dihydro-1H-inden-1-aminium tetrafluoroborate; (1S,2S)-2-(Diphenylphosphino)-1-aminoindane tetrafluoroborate salt; (S,S)-2-(Diphenylphosphino)-1-aminoindane HBF4 salt; (1S,2S)-2-(Diphenylphosphino)indan-1-aminium tetrafluoroborate; (S,S)-Ph-Inda-BF4; (S,S)-IndaPhos tetrafluoroborate salt; Chiral indanylphosphine aminium salt; (1S,2S)-1-Amino-2-(diphenylphosphino)indane tetrafluoroborate
EINECS	Contact for details

Quality Control

Our (1S,2S)-2-(Diphenylphosphino)-2,3-Dihydro-1H-Inden-1-Aminiumtetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity (Min. 97%), and chiral integrity meet the specifications required for sensitive catalytic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or ambient temperature will degrade product quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.