Description

Endo-7-Boc-7-Azabicyclo[2.2.1]Heptan-2-Yl Benzylcarbamate Racemate is a high-purity, protected bicyclic amine derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Asymmetric Synthesis: Employed in the preparation of enantiomerically pure compounds due to its rigid bicyclic framework, which can induce high stereoselectivity.
• Peptidomimetic Development: Serves as a conformationally restricted proline or piperidine analog in the design of novel peptide-like molecules.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke intermediates for client projects.

Basic Information

Item	Details
Product Name	Endo-7-Boc-7-Azabicyclo[2.2.1]Heptan-2-Yl Benzylcarbamate Racemate
CAS No.	1221818-02-5
Molecular Formula	C19H26N2O4
Molecular Weight	346.43 g/mol
Synonyms	7-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 7-[[(1,1-dimethylethoxy)carbonyl]-, phenylmethyl ester, endo-; 7-Boc-7-azabicyclo[2.2.1]heptan-2-yl benzylcarbamate; Benzyl (1R,2S,4S)-7-[(tert-butoxycarbonyl)amino]-7-azabicyclo[2.2.1]heptane-2-carboxylate (racemic); 7-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 7-[(tert-butoxycarbonyl)amino]-, benzyl ester, endo-; 7-Boc-2-endo-(benzyloxycarbonyl)-7-azabicyclo[2.2.1]heptane; Bicyclic Proline Derivative; Bicyclic Amine Building Block.
EINECS	Contact for details

Quality Control

Our Endo-7-Boc-7-Azabicyclo[2.2.1]Heptan-2-Yl Benzylcarbamate Racemate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements, supporting development from research to pre-clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or with appropriate desiccant to maintain stability. For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Racemic mixture (50:50 enantiomeric ratio)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.