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(Rp)-1-[(S)-tert-Butylphosphinoyl]-2-[(S)-1-(Diphenylphosphino)Ethyl]Ferrocene CAS NO 1221746-31-1


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CAS No.:1221746-31-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(Rp)-1-[(S)-tert-Butylphosphinoyl]-2-[(S)-1-(Diphenylphosphino)Ethyl]Ferrocene is a highly sophisticated, chiral ferrocenyl phosphine ligand designed for asymmetric catalysis. This compound is valued for its ability to impart exceptional enantioselectivity and catalytic activity in transition metal-catalyzed reactions, enabling the production of high-purity chiral intermediates. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop efficient and selective synthetic routes.

Application

  • As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
  • Critical component in rhodium- and ruthenium-catalyzed reactions for producing enantiomerically pure pharmaceutical actives.
  • Catalyst for asymmetric C-C bond-forming reactions, including cross-coupling and allylic substitution.
  • Use in the synthesis of chiral agrochemicals and flavors & fragrances.
  • Research and development of novel homogeneous catalytic processes in academic and industrial settings.
  • Production of optically active fine chemicals and advanced materials.

Basic Information

Item Details
Product Name (Rp)-1-[(S)-tert-Butylphosphinoyl]-2-[(S)-1-(Diphenylphosphino)Ethyl]Ferrocene
CAS No. 1221746-31-1
Molecular Formula C28H32FeOP2
Molecular Weight 486.34 g/mol
Synonyms (Rp,S,S)-1-(tert-Butylphosphinyl)-2-[1-(diphenylphosphino)ethyl]ferrocene; Josiphos SL-J009-1 type ligand; Chiral Ferrocenylphosphine Ligand; (Rp)-1-[(S)-tert-Butylphosphinyl]-2-[(S)-1-(diphenylphosphino)ethyl]ferrocene; (Rp,S,S)-Taniaphos; (Rp,S,S)-1-(tert-Butylphosphinoyl)-2-[1-(diphenylphosphino)ethyl]ferrocene
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Quality Control

Every batch of our chiral ligands is produced and tested under strict quality management to ensure consistent high performance in sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identity confirmation via spectroscopic methods. Our quality systems support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. Allow the container to reach room temperature in a dry environment before opening to minimize moisture condensation.

Specification

Item Specification
Appearance Orange to red powder or crystals
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Heavy Metals < 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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