Description

1-(Benzyloxy)-3-Bromo-5-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic ether building block designed for advanced chemical synthesis. This compound is valued for its unique trifluoromethoxy and bromo substituents, which introduce both lipophilicity and sites for further functionalization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine substituent, enabling the construction of complex biaryl structures.
• Fluorine Chemistry Studies: Acts as a model compound for studying the influence of the trifluoromethoxy group on electronic properties and reactivity in aromatic systems.

Basic Information

Product Name	1-(Benzyloxy)-3-Bromo-5-(Trifluoromethoxy)Benzene
CAS No.	1221658-68-9
Molecular Formula	C14H10BrF3O2
Molecular Weight	347.13 g/mol
Synonyms	3-Bromo-5-(trifluoromethoxy)phenyl benzyl ether; Benzene, 1-(benzyloxy)-3-bromo-5-(trifluoromethoxy)-; 1-Bromo-3-(benzyloxy)-5-(trifluoromethoxy)benzene; 3-Bromo-5-(trifluoromethoxy) benzyloxybenzene; 1-(Benzyloxy)-3-bromo-5-(trifluoromethoxy)benzene; BTFB (abbreviation); 3-Br-5-OCF3 Benzyloxybenzene
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxy)-3-Bromo-5-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.