Description

4-Bromo-1H-Pyrrole-2-Carbonitrile is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and novel agrochemicals.

Application

• Pharmaceutical Intermediate: A critical synthon for the construction of pyrrole-containing drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that leverage the pyrrole scaffold for bioactivity.
• Material Science Research: Serves as a building block for organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed in the synthesis of specialized probes and linkers for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	4-Bromo-1H-Pyrrole-2-Carbonitrile
CAS No.	1221435-18-2
Molecular Formula	C5H3BrN2
Molecular Weight	170.99 g/mol
Synonyms	4-Bromo-1H-pyrrole-2-carbonitrile; 2-Cyano-4-bromopyrrole; 4-Bromo-2-cyanopyrrole; 4-Bromopyrrole-2-carbonitrile; 1H-Pyrrole-2-carbonitrile, 4-bromo-; 4-Bromo-2-pyrrolecarbonitrile; 4-Bromo-1H-pyrrol-2-yl cyanide
EINECS	Contact for details

Quality Control

Our 4-Bromo-1H-Pyrrole-2-Carbonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.