Description

2-Amino-N-(tert-Butyl)-2-Methylpropanamide Hydrochloride is a high-purity, specialized organic intermediate primarily used in advanced pharmaceutical synthesis and fine chemical research. Its value lies in its role as a key building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel chemical entities. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for scalable synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for candidates targeting neurological or metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require a sterically hindered amine moiety.
• Peptidomimetics & Bioactive Molecule Synthesis: Serves as a precursor for creating peptide analogs and other bioactive compounds where the tert-butyl group provides metabolic stability.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal complexes.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polyamides and other performance polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.

Basic Information

Product Name	2-Amino-N-(tert-Butyl)-2-Methylpropanamide Hydrochloride
CAS No.	1220037-14-8
Molecular Formula	C9H21ClN2O
Molecular Weight	208.73 g/mol
Synonyms	2-Amino-N-tert-butyl-2-methylpropanamide hydrochloride; 2-Amino-2-methyl-N-(tert-butyl)propanamide HCl; 2-Methyl-2-[(tert-butylamino)carbonyl]aminopropane hydrochloride; tert-Butyl 2-amino-2-methylpropionamide hydrochloride; 2-Amino-N-(1,1-dimethylethyl)-2-methylpropanamide hydrochloride; 2-Amino-2-methyl-N-(2-methyl-2-propanyl)propanamide hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-N-(tert-Butyl)-2-Methylpropanamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.