Description

3-(2-Fluoroethoxy)Pyrrolidine Hydrochloride is a high-purity, fluorinated pyrrolidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique fluorine-containing ethoxy side chain into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder therapies.
• Agrochemical Synthesis: Used as a building block for creating novel pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Material Science Research: Acts as a monomer or modifier in the development of specialty polymers and advanced materials.
• Process Chemistry & Scale-up: Supplied for route scouting, optimization, and pilot-scale production of target molecules.

Basic Information

Product Name	3-(2-Fluoroethoxy)Pyrrolidine Hydrochloride
CAS No.	1219979-95-9
Molecular Formula	C6H13ClFNO
Molecular Weight	169.62 g/mol
Synonyms	3-(2-Fluoroethoxy)pyrrolidine HCl; 3-(2-Fluoroethoxy)-1-azacyclopentane hydrochloride; Pyrrolidine, 3-(2-fluoroethoxy)-, hydrochloride (1:1); 1-Azacyclopentane-3-ethanol, β-fluoro-, hydrochloride; 3-(β-Fluoroethoxy)pyrrolidine hydrochloride; 3-(2-Fluoroethoxy)azolidine hydrochloride; 3-(2-Fluoroethoxy)pyrrolidine, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(2-Fluoroethoxy)Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.