Description

Chlorpheniramine-D6 Maleate Salt is a stable isotope-labeled analog of the classic antihistamine, chlorpheniramine maleate. This deuterated compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reliability in analytical methods. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities for pharmacokinetic studies, bioanalytical method development, and drug metabolism research.

Application

• Internal Standard for LC-MS/MS analysis in bioanalytical studies.
• Quantitative reference material for pharmacokinetic (PK) and pharmacodynamic (PD) research.
• Method development and validation in clinical and forensic toxicology.
• Metabolite identification and drug metabolism studies.
• Quality control and assurance in pharmaceutical manufacturing of antihistamine products.
• Use in stable isotope dilution assays for high-precision quantification.

Basic Information

Product Name	Chlorpheniramine-D6 Maleate Salt
CAS No.	1219806-45-7
Molecular Formula	C20H19D6ClN2O4
Molecular Weight	394.89 g/mol (approx.)
Synonyms	Chlorpheniramine-d6 maleate; (+/-)-Chlorpheniramine-d6 maleate salt; 2-[p-Chloro-α-[2-(dimethyl-d6)amino]ethyl]benzyl]pyridine maleate (1:1); Deutrated Chlorpheniramine Maleate; Chlorphenamine-D6 Maleate; DL-Chlorpheniramine-D6 Maleate; Isotope-labeled Chlorpheniramine Maleate
EINECS	Contact for details

Quality Control

Our Chlorpheniramine-D6 Maleate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm isotopic purity, chemical purity, and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research and quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D6)	≥98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.