Description

2,6-Di-(tert-Butyl-D9)-4-Methoxyphenol-3,5-D2 CAS NO 1219799-34-4 is a deuterated isotopologue of the common antioxidant butylated hydroxyanisole (BHA). This compound is specifically engineered for use as an internal standard in analytical chemistry, providing unmatched accuracy for quantification and metabolic studies. It is essential for researchers and quality control laboratories in the pharmaceutical, food science, and material stability sectors who require precise, interference-free measurement of antioxidant levels.

Application

• Analytical Internal Standard: Primary use as a deuterated standard for Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis of BHA and related phenolic antioxidants.
• Pharmaceutical Research: Enables precise pharmacokinetic and metabolic fate studies of antioxidant additives in drug formulations and active pharmaceutical ingredients (APIs).
• Food & Beverage Analysis: Critical for accurate quantification of BHA in food products, ensuring compliance with global food safety regulations (e.g., FDA, EFSA).
• Polymer & Material Science: Used to study the degradation pathways and stabilization efficiency of antioxidants in plastics, rubbers, and fuels.
• Reference Material: Serves as a high-purity certified reference material (CRM) for calibrating analytical instruments and validating methods.
• Isotope Dilution Mass Spectrometry (IDMS): The gold-standard technique for achieving the highest possible accuracy in quantitative analysis, where this compound is indispensable.

Basic Information

Item	Detail
Product Name	2,6-Di-(tert-Butyl-D9)-4-Methoxyphenol-3,5-D2
CAS No.	1219799-34-4
Molecular Formula	C16D20O2
Molecular Weight	260.42 g/mol
Synonyms	BHA-d20; 2,6-Bis(tert-butyl-d9)-4-methoxyphenol-3,5-d2; Deuterated Butylated Hydroxyanisole; 3,5-Dideuterio-2,6-bis[(1,1-dimethylethyl-d9)]-4-methoxyphenol; Isotopically Labeled BHA; (3,5-D2, tert-butyl-D18)-BHA; Internal Standard for BHA; Antioxidant Standard-d20
EINECS	Contact for details

Quality Control

Every batch of our 2,6-Di-(tert-Butyl-D9)-4-Methoxyphenol-3,5-D2 is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting demands of analytical reference standards. Comprehensive testing includes NMR (1H, 13C, 2H) for isotopic enrichment verification and HPLC for chemical purity assessment. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (chemical purity)
Isotopic Enrichment	≥ 98 atom % D (by 2H NMR)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.