Description

Melperone-D4 Hydrochloride is a deuterated analog of the antipsychotic agent melperone, specifically labeled with four deuterium atoms. This stable isotopically labeled compound is a critical reference standard and internal standard in quantitative bioanalytical research, ensuring high accuracy and reliability in mass spectrometry-based assays. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in pharmacokinetic, metabolic, and forensic studies of melperone.

Application

• Pharmacokinetic and Bioavailability Studies: Serves as an internal standard for the precise quantification of melperone in biological matrices (plasma, serum, urine).
• Drug Metabolism Research (DMPK): Used to investigate the metabolic pathways and clearance rates of melperone in vitro and in vivo.
• Forensic and Clinical Toxicology: Enables accurate measurement of melperone levels for therapeutic drug monitoring or forensic analysis.
• Method Development and Validation: A key component in developing and validating robust LC-MS/MS and GC-MS analytical methods.
• Quality Control in Pharmaceutical Manufacturing: Acts as a certified reference material to ensure the accuracy of potency and impurity testing.

Basic Information

Product Name	Melperone-D4 Hydrochloride
CAS No.	1219798-80-7
Molecular Formula	C16H18D4ClNO • HCl
Molecular Weight	316.28 g/mol (approx.)
Synonyms	Melperone-d4 HCl; 1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone-d4 Hydrochloride; 4'-Fluoro-4-(4-methyl-1-piperidinyl)butyrophenone-d4 Hydrochloride; Buronil-d4; Methylperone-d4 Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Melperone-D4 Hydrochloride is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (chemical purity)
Isotopic Purity (NMR/MS)	≥98.0 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.