Description

Anagrelide (13 C 3) is a stable isotope-labeled analog of the pharmaceutical compound Anagrelide, specifically labeled with three carbon-13 atoms. This high-purity reference material is essential for ensuring the accuracy and reliability of quantitative analytical methods in pharmaceutical research and development. It is primarily used by scientists and quality control professionals in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors for applications requiring precise internal standardization.

Application

• Internal Standard for Bioanalytical Assays: Used as a quantitative reference in LC-MS/MS and GC-MS methods for the accurate measurement of Anagrelide and its metabolites in biological matrices like plasma and serum.
• Pharmacokinetic and Metabolism Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Method Development and Validation: Serves as a critical tool for developing, optimizing, and validating robust analytical methods compliant with GLP and GMP guidelines.
• Drug Impurity Profiling and Characterization: Aids in the identification and quantification of process-related impurities and degradation products in active pharmaceutical ingredient (API) batches.
• Stability-Indicating Assays: Used in forced degradation studies to monitor the stability of Anagrelide under various stress conditions.
• Certified Reference Material (CRM) Production: Acts as a primary standard for the preparation of secondary certified reference materials used in quality control laboratories.

Basic Information

Product Name	Anagrelide (13 C 3)
CAS No.	1219531-58-4
Molecular Formula	C10H7Cl2N3O 13C3
Molecular Weight	~ 280.10 g/mol (exact mass varies with isotopic enrichment)
Synonyms	6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one-13C3; Anagrelide-13C3; 13C3-Anagrelide; Isotopically Labeled Anagrelide; Anagrelide Internal Standard; [13C3]-Anagrelide; Anagrelide (carbon-13 labeled); BL-4162A-13C3
EINECS	Contact for details

Quality Control

Every batch of Anagrelide (13 C 3) is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to support its use in regulated environments. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as isotopic purity (atom % 13C), chemical purity (by HPLC), and confirmation of structure (by NMR and MS). Our quality commitment ensures consistency and traceability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the certificate of analysis. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99 atom % 13C
Chemical Purity	≥ 95% (by 1H-NMR)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.