Description

Boc-5-Methoxy-2-Methyl-Dl-Tryptophan is a protected derivative of the non-proteinogenic amino acid tryptophan, featuring both tert-butoxycarbonyl (Boc) and methoxy groups. This compound is a crucial building block in peptide synthesis and medicinal chemistry, where it serves as a key intermediate for introducing modified tryptophan motifs into target molecules. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of novel therapeutic agents and bioactive peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in oncology and neurology.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a methoxy-substituted tryptophan residue with a protected amine group.
• Medicinal Chemistry Research: Serves as a building block for creating compound libraries to study structure-activity relationships (SAR).
• Bioconjugation: The Boc-protected amine allows for selective deprotection and subsequent conjugation to other molecules, such as linkers or fluorescent dyes.
• Chemical Biology Probes: Utilized in the synthesis of probes for studying enzyme mechanisms or protein-protein interactions.
• Academic & Institutional Research: Employed in university and R&D lab settings for fundamental studies in organic synthesis and amino acid chemistry.

Basic Information

Product Name	Boc-5-Methoxy-2-Methyl-Dl-Tryptophan
CAS No.	1219410-28-2
Molecular Formula	C20H26N2O5
Molecular Weight	374.43 g/mol
Synonyms	N-Boc-5-Methoxy-2-methyl-DL-tryptophan; (RS)-2-((tert-Butoxycarbonyl)amino)-3-(5-methoxy-2-methyl-1H-indol-3-yl)propanoic acid; 5-Methoxy-2-methyl-DL-tryptophan N-Boc derivative; Boc-5-MeO-2-Me-DL-Trp-OH; DL-2-Methyl-5-methoxytryptophan N-Boc; tert-Butyl (1-((5-methoxy-2-methyl-1H-indol-3-yl)methyl)-1-carboxyethyl)carbamate; N-(tert-Butoxycarbonyl)-5-methoxy-2-methyl-DL-tryptophan
EINECS	Contact for details

Quality Control

Our Boc-5-Methoxy-2-Methyl-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is soluble in strong acids and organic solvents; ensure the storage area is compatible with these materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.