Description

Di-Boc-α-Methyl-Dl-Ornithine is a protected derivative of the non-proteinogenic amino acid ornithine, featuring two tert-butoxycarbonyl (Boc) protecting groups and an α-methyl substitution. This compound is a critical building block in advanced organic synthesis, particularly for the preparation of complex peptides and peptidomimetics where precise stereochemistry and functional group manipulation are required. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, especially those targeting enzyme inhibition.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate modified ornithine residues, enabling the study of structure-activity relationships.
• Biochemical Research: Acts as a precursor or inhibitor analog in metabolic pathway studies, particularly those involving polyamine biosynthesis.
• Protecting Group Strategy: The Boc groups allow for selective deprotection, making it valuable for multi-step synthetic sequences in medicinal chemistry.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Di-Boc-α-Methyl-Dl-Ornithine
CAS No.	1219378-96-7
Molecular Formula	C₁₆H₃₀N₂O₆
Molecular Weight	346.42 g/mol
Synonyms	N²,N⁵-Bis(tert-butoxycarbonyl)-α-methyl-DL-ornithine; Di-tert-butyl N-(1-((tert-butoxycarbonyl)amino)-3-methyl-1-oxobutan-2-yl)carbamate; α-Methyl-DL-ornithine di-Boc derivative; DL-α-Methylornithine di-Boc; Boc-α-Me-DL-Orn(Boc)-OH; (RS)-2-((tert-Butoxycarbonyl)amino)-5-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Di-Boc-α-Methyl-Dl-Ornithine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.