Description

Fmoc-Dl-(2-Bromophenyl)Glycine CAS NO 1219346-87-8 is a specialized, non-natural amino acid derivative designed for advanced peptide synthesis and pharmaceutical research. This compound is a critical building block for introducing the unique (2-bromophenyl)glycine moiety into peptide chains, enabling the creation of novel structures with tailored biological activity and physicochemical properties. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for drug discovery, proteomics, and the development of peptide-based therapeutics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc/tert-butyl strategy, facilitating the automated synthesis of complex peptides.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Peptidomimetic Design: Used to create peptide analogs and mimetics with enhanced stability, bioavailability, or receptor binding affinity by incorporating the brominated aromatic side chain.
• Chemical Biology Probes: Enables the synthesis of labeled or modified peptides for studying protein-protein interactions, enzyme mechanisms, and cellular pathways.
• Agrochemical Research: Employed in the development of novel peptide-based pesticides or growth regulators.
• Material Science: Potential use in the synthesis of functionalized polymers or supramolecular assemblies with specific electronic or structural properties.

Basic Information

Product Name	Fmoc-Dl-(2-Bromophenyl)Glycine
CAS No.	1219346-87-8
Molecular Formula	C23H18BrNO4
Molecular Weight	452.30 g/mol
Synonyms	Fmoc-(2-Br-Phg)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-(2-bromophenyl)glycine; Fmoc-2-Bromophenylglycine; Fmoc-DL-2-Bromophenylglycine; N-Fmoc-2-(2-Bromophenyl)glycine; (RS)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-2-(2-bromophenyl)acetic acid; DL-Fmoc-2-Bromophenylglycine; 2-Bromophenylglycine Fmoc derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Dl-(2-Bromophenyl)Glycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, chiral purity, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.