Description

Rac 3-(1,2,4-Triazol-1-Yl)-L-Alanine-15N,D2 is a stable isotope-labeled derivative of a triazole-substituted alanine amino acid analog. This compound is specifically designed for advanced research applications where precise molecular tracking and quantification are paramount. It is an essential tool for scientists in pharmaceutical development, agrochemical research, and metabolic studies who require high-purity, isotopically labeled building blocks for mass spectrometry, NMR spectroscopy, and tracer experiments.

Application

• Pharmaceutical Research & Development: Used as a labeled intermediate in the synthesis of novel drug candidates, particularly for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Metabolic Pathway Analysis: Serves as a tracer in biochemical research to elucidate metabolic pathways and enzyme mechanisms involving amino acid analogs.
• Mass Spectrometry Standards: Acts as an internal standard for the accurate quantification of unlabeled triazole-alanine compounds or related metabolites in complex biological matrices via LC-MS/MS.
• Agrochemical Research: Employed in the development and environmental fate studies of triazole-containing pesticides and fungicides.
• NMR Spectroscopy: The 15N and D (deuterium) labels provide distinct signals for structural elucidation and dynamic studies in solution.
• Chemical Biology Probes: Utilized to create labeled probes for investigating protein-ligand interactions and biological target engagement.

Basic Information

Item	Detail
Product Name	Rac 3-(1,2,4-Triazol-1-Yl)-L-Alanine-15N,D2
CAS No.	1219176-41-6
Molecular Formula	C5H6D215N3O2
Molecular Weight	Contact for details
Synonyms	DL-3-(1H-1,2,4-Triazol-1-yl)alanine-15N,d2; (±)-3-(1,2,4-Triazol-1-yl)alanine-15N,d2; 3-(1H-1,2,4-Triazol-1-yl)-DL-alanine-15N,d2; Alanine, 3-(1,2,4-triazol-1-yl)-, 15N,d2-labeled; Isotopically labeled triazole alanine; 15N, D2-Triazole alanine
EINECS	Contact for details

Quality Control

Every batch of Rac 3-(1,2,4-Triazol-1-Yl)-L-Alanine-15N,D2 is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with each shipment to ensure full traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (15N)	≥ 98 atom %
Isotopic Enrichment (D)	≥ 98 atom % (D2)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.