Description

Fmoc-3-Fluoro-Dl-Valine CAS NO 1219144-82-7 is a protected, non-natural amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for introducing fluorinated valine analogs into peptide chains, enabling the study of structure-activity relationships and enhancing metabolic stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for incorporating fluorinated valine residues into custom peptide sequences.
• Pharmaceutical Research: For the development of peptide drugs with improved bioavailability and resistance to enzymatic degradation.
• Chemical Biology Studies: Used to create fluorinated peptide analogs for probing protein-protein interactions and enzyme mechanisms.
• Proteomics & Bioconjugation: Serves as a specialized reagent for labeling peptides or creating affinity tags.
• Material Science: Potential use in the synthesis of fluorinated biomaterials and polymers with unique properties.

Basic Information

Product Name	Fmoc-3-Fluoro-Dl-Valine
CAS No.	1219144-82-7
Molecular Formula	C₂₁H₂₂FNO₄
Molecular Weight	371.41 g/mol
Synonyms	Fmoc-3-Fluoro-DL-valine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-fluoro-DL-valine; 3-Fluoro-DL-valine, N-Fmoc derivative; Fmoc-3-F-Val-OH; N-Fmoc-3-fluorovaline; (RS)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-fluoro-3-methylbutanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-3-Fluoro-Dl-Valine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify the DL-mixture. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.