Description

2,7-Bis(Alloxycarbonylamino)-9-(Biotinylaminoethylamino)Acridine is a sophisticated, multi-functional acridine derivative engineered for advanced biochemical and diagnostic applications. This compound matters because it combines the intercalating properties of an acridine core with the high-affinity biotin-streptavidin binding system, creating a powerful tool for targeted labeling and detection. It is primarily needed by researchers and manufacturers in the fields of molecular diagnostics, fluorescence in situ hybridization (FISH), and advanced bioconjugation for developing sensitive assays and probes.

Application

• Fluorescent Probes & Labels: Used as a high-sensitivity fluorescent tag in FISH assays for chromosomal analysis and pathogen detection.
• Nucleic Acid Staining & Detection: Serves as an intercalating dye for visualizing DNA/RNA in gels and microarrays, with signal amplification via biotin.
• Bioconjugation & Linker Chemistry: Acts as a versatile heterobifunctional linker for attaching biomolecules (like antibodies or oligonucleotides) to surfaces or other proteins via the biotin handle.
• Diagnostic Kit Development: A key component in the formulation of diagnostic kits for genetic testing, oncology, and infectious diseases.
• Research Reagents: Employed in academic and industrial R&D for studying nucleic acid-protein interactions and developing novel bioanalytical methods.
• Avidin/Biotin-Based Assays: Utilized in ELISA, immunohistochemistry, and other assay formats that leverage the strong biotin-streptavidin interaction for signal enhancement.

Basic Information

Product Name	2,7-Bis(Alloxycarbonylamino)-9-(Biotinylaminoethylamino)Acridine
CAS No.	1219125-65-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	9-[(2-Aminoethyl)amino]-2,7-bis(alloxycarbonylamino)acridine biotin conjugate; Biotinylated Acridine Derivative; Acridine-biotin conjugate; 2,7-Bis(carbamoyloxy)-9-(2-biotinamidoethylamino)acridine (related structure); FISH Probe Labeling Reagent; Biotin-XX acridine; Diagnostic Acridine Dye
EINECS	Contact for details

Quality Control

Our 2,7-Bis(Alloxycarbonylamino)-9-(Biotinylaminoethylamino)Acridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and functional validation in relevant assay systems. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF
Functional Activity	Validated in model assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.