Description

3,5-Dichloro-4-isopropoxyphenylboronic acid is a high-purity organoboron compound, specifically a functionalized phenylboronic acid derivative. This chemical serves as a critical Suzuki-Miyaura cross-coupling reagent, enabling the formation of carbon-carbon bonds in complex molecule synthesis. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise building blocks for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides, contributing to crop protection solutions.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as polymers for OLEDs and sensors.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and inhibitors that interact with biomolecules containing diol groups, leveraging boronic acid chemistry.
• Ligand Synthesis for Catalysis: Acts as a precursor for creating sophisticated bidentate or tridentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	3,5-Dichloro-4-isopropoxyphenylboronic Acid
CAS No.	1218790-62-5
Molecular Formula	C9H11BCl2O3
Molecular Weight	249.90 g/mol
Synonyms	(3,5-Dichloro-4-isopropoxyphenyl)boronic acid; B-(3,5-Dichloro-4-isopropoxyphenyl)boronic acid; 4-Isopropoxy-3,5-dichlorophenylboronic acid; 3,5-Dichloro-4-(1-methylethoxy)benzeneboronic acid; Boronic acid, B-[3,5-dichloro-4-(1-methylethoxy)phenyl]-; 1218790-62-5; 3,5-Dichloro-4-propan-2-yloxyphenylboronic acid
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-4-isopropoxyphenylboronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding pharmaceutical and fine chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.