Description

1H-Indole-2-Carboxylic Acid, 5-Fluoro-3-Methyl-, Hydrazide is a high-purity, fluorinated indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a hydrazide moiety and a fluorine substituent, makes it a versatile intermediate for constructing complex heterocyclic systems with tailored properties. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the indole scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a probe or linker molecule in bioconjugation and target identification studies due to its reactive hydrazide group.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 5-Fluoro-3-Methyl-, Hydrazide
CAS No.	1217862-86-6
Molecular Formula	C10H10FN3O
Molecular Weight	207.21 g/mol
Synonyms	5-Fluoro-3-methyl-1H-indole-2-carbohydrazide; 5-Fluoro-3-methylindole-2-carboxylic acid hydrazide; 1H-Indole-2-carboxylic acid, 5-fluoro-3-methyl-, hydrazide; 3-Methyl-5-fluoroindole-2-carbohydrazide; (5-Fluoro-3-methyl-1H-indol-2-yl)formohydrazide
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-2-Carboxylic Acid, 5-Fluoro-3-Methyl-, Hydrazide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.