Description

n-[(R)-(+)-1-Phenylethyl]Imidazole-1-Carboxamide is a high-purity, chiral organic compound featuring a stereogenic center and an imidazole carboxamide functional group. This compound serves as a critical chiral intermediate or building block in advanced organic synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control in their synthetic routes.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing drugs targeting the central nervous system or as enzyme inhibitors.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of novel chiral ligands for asymmetric catalysis, enhancing reaction enantioselectivity.
• Agrochemical Research: Intermediate in creating enantiomerically pure agrochemicals, such as herbicides or fungicides, where specific stereochemistry impacts biological activity.
• Chemical Biology & Proteomics: Acts as a versatile handle or linker in chemical probe design for studying enzyme function and protein interactions.
• Material Science Research: Potential monomer or functional additive in the synthesis of specialty polymers with tailored optical or electronic properties.
• Academic & Process R&D: Serves as a reference standard or starting material for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	n-[(R)-(+)-1-Phenylethyl]Imidazole-1-Carboxamide
CAS No.	1217846-28-0
Molecular Formula	C12H13N3O
Molecular Weight	215.25 g/mol
Synonyms	(R)-1-Phenylethyl Imidazole-1-Carboxamide; (R)-(+)-1-Phenylethylimidazole-1-carboxamide; 1-[(1R)-1-Phenylethyl]-1H-imidazole-1-carboxamide; Imidazole-1-carboxylic acid (1R)-1-phenylethylamide; (R)-N-(1-Phenylethyl)imidazole-1-carboxamide; (R)-PEICA; 1-[(R)-α-Methylbenzyl]imidazole-1-carboxamide
EINECS	Contact for details

Quality Control

Our n-[(R)-(+)-1-Phenylethyl]Imidazole-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee reliable and reproducible performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.