Description

(R)-(3-Pyrrolidin-2-Yl-Propyl)-Carbamic Acid tert-Butyl Ester CAS NO 1217838-01-1 is a high-purity chiral intermediate featuring a protected amine group on a pyrrolidine scaffold. This compound is critical for ensuring the stereochemical integrity and successful synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas like central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potent, stereospecific drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in research-scale and process chemistry for constructing complex molecular architectures.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed in reactions requiring high enantiomeric purity due to its defined (R)-configuration.
• Peptidomimetics Research: Useful for introducing constrained, nitrogen-containing heterocycles into peptide analogs.
• Ligand and Catalyst Preparation: Can be utilized to develop novel chiral ligands for catalytic applications.

Basic Information

Item	Details
Product Name	(R)-(3-Pyrrolidin-2-Yl-Propyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1217838-01-1
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	(R)-tert-Butyl (3-(pyrrolidin-2-yl)propyl)carbamate; (R)-N-Boc-3-(2-pyrrolidinyl)propylamine; (R)-1-Boc-amino-3-(2-pyrrolidinyl)propane; (R)-3-(2-Pyrrolidinyl)-1-propylamine, N-Boc-protected; (R)-N-(tert-Butoxycarbonyl)-3-(2-pyrrolidinyl)propylamine; (R)-Boc-NH-(CH2)3-pyrrolidine; (R)-2-(3-((tert-Butoxycarbonyl)amino)propyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-(3-Pyrrolidin-2-Yl-Propyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.