Description

(2S)-n-(2-Boc-Amino-3-Phenylpropyl) Boc-Glycine is a specialized, high-purity Boc-protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for the controlled assembly of complex peptides and peptidomimetics, offering precise stereochemistry and protecting group compatibility. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including peptide-based drugs and protease inhibitors.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential addition of glycine in complex peptide chains.
• Pharmaceutical Research & Development: Serves as a crucial building block for synthesizing peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Design: Used in the construction of peptidomimetic scaffolds that mimic natural peptide substrates.
• Chemical Biology Probes: Enables the synthesis of labeled or modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Custom Peptide Services: A vital raw material for CROs and CDMOs offering bespoke peptide manufacturing.
• Academic Research: Supports synthetic chemistry projects focused on novel methodologies and bioactive compound discovery.

Basic Information

Item	Details
Product Name	(2S)-n-(2-Boc-Amino-3-Phenylpropyl) Boc-Glycine
CAS No.	1217833-76-5
Molecular Formula	C21H32N2O6
Molecular Weight	408.49 g/mol
Synonyms	Boc-Gly-(S)-BAPA-OH; N-[(2S)-2-[[(tert-Butoxy)carbonyl]amino]-3-phenylpropyl]-N-[(tert-butoxy)carbonyl]glycine; Boc-Gly-BAPA(Boc)-OH; tert-Butyl N-[(2S)-2-[[(tert-butoxy)carbonyl]amino]-3-phenylpropyl]-N-[(tert-butoxy)carbonyl]glycinate; (S)-N-(2-(Boc-amino)-3-phenylpropyl)-Boc-glycine; Glycine, N-[(1S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-(phenylmethyl)ethyl]-N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our (2S)-n-(2-Boc-Amino-3-Phenylpropyl) Boc-Glycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral HPLC for enantiomeric excess, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.