Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2-Fluoro-4-Chlorophe is a specialized, high-purity chemical building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise chirality and functional group compatibility in complex molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including peptide-based therapeutics and targeted crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced, targeted herbicides and pesticides where specific stereochemistry is required for efficacy.
• Peptide Chemistry: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Protecting Group Reagent: The Fmoc (Fluorenylmethyloxycarbonyl) moiety is widely employed for the temporary protection of amine groups during multi-step syntheses.
• Bioconjugation: Useful in the development of antibody-drug conjugates (ADCs) and other biopharmaceutical linker systems.
• Material Science Research: Employed in the synthesis of specialized monomers for advanced polymeric materials.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2-Fluoro-4-Chlorophe
CAS No.	1217768-67-6
Molecular Formula	C22H15ClFNO4
Molecular Weight	411.81 g/mol
Synonyms	Fmoc-D-2-Fluoro-4-chlorophenylalanine; Fmoc-2-F-4-Cl-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-2-fluoro-4-chlorophenylalanine; (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(2-fluoro-4-chlorophenyl)propanoic acid; Fmoc-D-2-F-4-Cl-Phe; N-Fmoc-D-2-fluoro-4-chlorophenylalanine; Fmoc-D-4-Chloro-2-fluorophenylalanine
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2-Fluoro-4-Chlorophe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.