Description

(2S)-2-Amino-n-Cyclopentylpropanamide CAS NO 1217767-70-8 is a chiral, non-natural amino acid derivative featuring a cyclopentyl amide moiety. This compound is a high-value intermediate of significant interest in modern pharmaceutical research and development, particularly for its role in constructing peptidomimetics and bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in protease inhibitor and other small-molecule drug candidates.
• Peptidomimetic Research: Used to create peptide analogs with enhanced metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study enzyme function and biological pathways.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis to introduce the (S)-2-aminopropanamide configuration.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the drug discovery pipeline.

Basic Information

Product Name	(2S)-2-Amino-n-Cyclopentylpropanamide
CAS No.	1217767-70-8
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	(S)-2-Amino-N-cyclopentylpropanamide; L-Alaninamide, N-cyclopentyl-; N-Cyclopentyl-L-alaninamide; (S)-2-Amino-N-cyclopentylpropionamide; (2S)-2-Amino-N-cyclopentylpropanamide; (S)-α-Aminopropionylcyclopentylamine; Cyclopentylamide of (S)-2-aminopropanoic acid
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-n-Cyclopentylpropanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.