Description

(2S)-2-Amino-3-[1-[(2-Methylpropan-2-Yl)Oxycarbonyl]Piperidin-4-Yl]Propanoic Acid is a high-purity, protected amino acid derivative featuring a piperidine scaffold and a tert-butoxycarbonyl (Boc) protecting group. This compound is a critical building block in modern pharmaceutical research and development, enabling the synthesis of complex molecules with precise stereochemistry. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of novel therapeutic agents, particularly in peptide mimetics and small molecule drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) targeting neurological disorders, metabolic diseases, and oncology.
• Peptidomimetic Research: Serves as a constrained, non-natural amino acid analog for designing and synthesizing peptide mimetics with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Used in the development of labeled compounds and molecular probes for studying enzyme mechanisms and receptor-ligand interactions.
• Process Chemistry: Employed in route scouting and optimization for the scalable, GMP-compliant manufacturing of candidate drugs.
• Library Synthesis: A valuable component in combinatorial chemistry for generating diverse compound libraries for high-throughput screening.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(2S)-2-Amino-3-[1-[(2-Methylpropan-2-Yl)Oxycarbonyl]Piperidin-4-Yl]Propanoic Acid
CAS No.	1217755-45-7
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	Boc-4-Piperidine-L-alanine; (S)-2-((tert-Butoxycarbonyl)amino)-3-(piperidin-4-yl)propanoic acid; Boc-L-4-Piperidylalanine; 1-Boc-4-(2-amino-2-carboxyethyl)piperidine (L-form); L-1-Boc-4-piperidylalanine; tert-Butyl (S)-4-(2-amino-2-carboxyethyl)piperidine-1-carboxylate; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(1-piperidinyl)propanoic Acid; 1217755-45-7
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-3-[1-[(2-Methylpropan-2-Yl)Oxycarbonyl]Piperidin-4-Yl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.