Description

L-(-)-Epinephrine-D3 is a deuterium-labeled isotopologue of the essential neurotransmitter and hormone epinephrine, specifically designed for use as an internal standard in analytical chemistry. This high-purity compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in complex biological matrices. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, clinical diagnostics, and life science sectors for applications such as pharmacokinetic studies and biomarker validation.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of epinephrine in biological samples (plasma, serum, urine).
• Metabolic pathway tracing and stable isotope dilution analysis in pharmacological research.
• Quality control and method development in pharmaceutical analysis for epinephrine-based drug products.
• Clinical diagnostics for accurate measurement of catecholamine levels in endocrine disorder testing.
• Biomedical research investigating the role and kinetics of epinephrine in neurological and cardiovascular systems.
• Calibration standard for high-precision analytical instrumentation in contract research organizations (CROs).

Basic Information

Product Name	L-(-)-Epinephrine-D3
CAS No.	1217733-17-9
Molecular Formula	C9H10D3NO3
Molecular Weight	186.22 g/mol (approx.)
Synonyms	(-)-Epinephrine-d3; L-Adrenaline-d3; (R)-(-)-Adrenaline-d3; 4-[1-Hydroxy-2-(methyl-d3-amino)ethyl]benzene-1,2-diol; Levo-Epinephrine-d3; Deuterated Epinephrine; Epinephrine Internal Standard; 1-(3,4-Dihydroxyphenyl)-2-(methyl-d3-amino)ethanol
EINECS	Contact for details

Quality Control

Our L-(-)-Epinephrine-D3 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment, and impurity profiles. We adhere to relevant industry guidelines to support research and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere to minimize oxidation and ensure long-term stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.