Description

Abacavir D4 CAS NO 1217731-56-0 is a deuterated internal standard of the nucleoside reverse transcriptase inhibitor Abacavir, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is critical for ensuring the accuracy and reliability of quantitative mass spectrometry analysis in pharmaceutical research and development. It is an essential tool for scientists and quality control laboratories in the pharmaceutical and contract research organization (CRO) sectors who require precise bioanalytical measurements for pharmacokinetic studies, drug metabolism research, and ensuring regulatory compliance.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative internal standard in Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) for the accurate measurement of Abacavir in biological matrices.
• Pharmacokinetic and Bioavailability Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in clinical and pre-clinical trials.
• Drug Metabolism Research: Used in metabolite identification and profiling studies to understand the biotransformation pathways of Abacavir.
• Quality Control and Assurance: Supports method development and validation in pharmaceutical QC labs to ensure batch-to-batch consistency and product safety.
• Forensic and Doping Control Analysis: Applicable in specialized testing environments for the definitive identification and quantification of the parent compound.

Basic Information

Product Name	Abacavir D4
CAS No.	1217731-56-0
Molecular Formula	C14H14D4N6O
Molecular Weight	274.33 g/mol
Synonyms	Abacavir-d4; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol-d4; [(1S,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol-d4; Ziagen-d4; ABC-d4; Cyclopropylaminopurine nucleoside analog-d4
EINECS	Contact for details

Quality Control

Every batch of Abacavir D4 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support your research, including proof of structure and isotopic purity. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as chemical purity, isotopic enrichment, and chromatographic profile. Our quality commitment ensures the material meets the high standards required for sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (H-NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98.0 atom % D
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.